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Phase 2 trial data (published in New England Journal of Medicine, 2023 ): 24.2% average weight loss at 48 weeks with 12 mg dose 22.8% with 8 mg dose Placebo group lost 2.1% Most recent Phase 3 trial data (TRIUMPH-4, December 2025): 28.7% average weight loss at 68 weeks with 12 mg dose 26.4% with 9 mg dose 58.6% of participants on 12 mg achieved at least 25% weight loss 39.4% achieved at least 30% weight loss For context: These are the highest weight loss numbers reported in any clinical trial for a pharmacological obesity treatment

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The growth hormone peptide field has evolved significantly since sermorelins approval in the late 1990s, and the combination of CJC-1295 with Ipamorelin represents a clinically superior option for most adults pursuing growth hormone optimization in 2026

Consult a doctor After an one-on-one counseling session, the doctor will provide an online consultation via phone call

Ben: Welcome to season 14, episode 1 of Acquired, the podcast about great companies and the stories and playbooks behind them

For researchers considering a switch between medications, understanding these storage parallels is important